A100 vs AMD MI300X: Specs, VRAM & Price
Short answer: choose the AMD MI300X when 192 GB of VRAM is the gating requirement. Choose the A100 when 80 GB is enough for the workload and the lower hourly rate points that way.
The A100 has 80 GB of VRAM; the AMD MI300X has 192 GB.
You can rent both by the hour, no purchase required. A100 from $1.10/GPU/hr; AMD MI300X from $3.29/GPU/hr. The A100 is 66% cheaper at the entry rate.
A100
Good for training and inference on models that don't need FP8 kernels
AMD MI300X
Good for training and serving frontier-scale LLMs
Last updated: 2026-10-16 UTCRefreshes every 6 hours
Specs side by side
| Spec | A100 | AMD MI300X |
|---|---|---|
| VRAM | 80 GB | 192 GB |
| Memory bandwidth | 2,039 GB/s | 5.3 TB/s |
| Architecture | Ampere | CDNA3 |
| Compute capability | 8.0 | n/a |
| Precisions in hardware | FP32, FP16, BF16, INT4 | FP32, FP16, BF16, FP8, INT4 |
| Peak FP16/BF16 tensor TFLOPS | 312 TFLOPS | 1,307.4 TFLOPS |
| Peak FP8 tensor TFLOPS | – | 2,614.9 TFLOPS |
| NVLink / multi-GPU interconnect | NVLink 3, 600 GB/s | Infinity Fabric |
| Max board power (TDP) | 400W (SXM) | 750W |
| Form factor | SXM4 | – |
| Regions | 5 | 1 |
On-demand price
| Rate | A100 | AMD MI300X |
|---|---|---|
| Lowest per GPU/hr | $1.50/GPU/hr | $3.29/GPU/hr |
Which is better for AI: A100 or AMD MI300X?
Choose the AMD MI300X when 192 GB of VRAM is the gating requirement. Choose the A100 when 80 GB is enough for the workload and the lower hourly rate points that way.
A100 vs AMD MI300X: common questions
Is the A100 or the AMD MI300X better for AI?
Short answer: choose the AMD MI300X when 192 GB of VRAM is the gating requirement. Choose the A100 when 80 GB is enough for the workload and the lower hourly rate points that way.
Is the A100 or the AMD MI300X cheaper to rent?
On Aquanode's live marketplace the A100 starts at $1.10/GPU/hr (median $1.65/GPU/hr) and the AMD MI300X starts at $3.29/GPU/hr (median $3.29/GPU/hr). The A100 is the cheaper of the two at the entry rate, by 66%.
What is the difference between the A100 and the AMD MI300X?
The A100 has 80 GB of VRAM against the AMD MI300X's 192 GB; the A100 is an Ampere part and the AMD MI300X is CDNA3; only the AMD MI300X supports FP8 compute. On price, the A100 lists from $1.10/GPU/hr and the AMD MI300X from $3.29/GPU/hr.
How widely available are the A100 and the AMD MI300X?
The A100 is listed in 5 regions and the AMD MI300X in 1 region right now.
How much does 1,000 GPU-hours cost on the A100 vs the AMD MI300X?
At the lowest rates listed today, 1,000 GPU-hours costs $1,102 on the A100 and $3,289 on the AMD MI300X, a difference of $2,187 for the same runtime. Rates are per GPU per hour and update hourly.
How much VRAM does the A100 have compared to the AMD MI300X?
The A100 has 80 GB of VRAM; the AMD MI300X has 192 GB.
Does the A100 or the AMD MI300X support NVLink?
Yes, both support a multi-GPU interconnect: the A100 has NVLink 3, 600 GB/s and the AMD MI300X has Infinity Fabric.
How this comparison is calculated
Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.
Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.
Memory bandwidth, tensor TFLOPS, NVLink/interconnect and max board power are the same verified-from-datasheet figures shown on each model's own A100 page and AMD MI300X page, which link the primary vendor source for that model. A dash here means Aquanode hasn't verified that figure from a primary source yet, never a guess.
Go further
Check what fits in each card's memory with the A100 VRAM calculator and the AMD MI300X VRAM calculator, see vendor-published throughput in the GPU benchmarks and specs table, or browse every model by generation in the GPU index.
More A100 comparisons
More AMD MI300X comparisons
Related reading: A100 pricing and specs, A100 vs H100, A100 vs V100, and The best GPUs for AI, ranked.
