AMD MI300X vs RTX 4080 Super: cloud rental cost compared

You can rent both by the hour, no purchase required. AMD MI300X from $2.99/GPU/hr across 1 provider; RTX 4080 Super from $0.280/GPU/hr across 2 providers. The RTX 4080 Super is 91% cheaper at the entry rate.

AMD MI300X
Good for training and serving frontier-scale LLMs
$2.99/hr
Lowest / GPU
$2.99/hr
Median / GPU
192 GB
VRAM
CDNA3
Architecture
RTX 4080 Super
Good for inference and light fine-tuning workloads
$0.280/hr
Lowest / GPU
$0.330/hr
Median / GPU
16 GB
VRAM
Ada Lovelace
Architecture

Specs side by side

Spec
AMD MI300X
RTX 4080 Super
VRAM
192 GB
16 GB
Architecture
CDNA3
Ada Lovelace
Compute capability
n/a
8.9
Precisions in hardware
FP32, FP16, BF16, FP8, INT4
FP32, FP16, BF16, FP8, INT4
Interconnect
PCIe
PCIe 4.0 x16
Lowest $/GPU/hr
$2.99
$0.280
Median $/GPU/hr
$2.99
$0.330
Providers
1
2
Regions
1
2

Price by provider

Provider
AMD MI300X $/GPU/hr
RTX 4080 Super $/GPU/hr
RunPod
$0.280
SimplePod
$0.380
Hot Aisle
$2.99

AMD MI300X vs RTX 4080 Super: common questions

Is the AMD MI300X or the RTX 4080 Super cheaper to rent?

On Aquanode's live marketplace the AMD MI300X starts at $2.99/GPU/hr (median $2.99/GPU/hr across 1 provider) and the RTX 4080 Super starts at $0.280/GPU/hr (median $0.330/GPU/hr across 2 providers). The RTX 4080 Super is the cheaper of the two at the entry rate, by 91%.

What is the difference between the AMD MI300X and the RTX 4080 Super?

The AMD MI300X has 192 GB of VRAM against the RTX 4080 Super's 16 GB; the AMD MI300X is a CDNA3 part and the RTX 4080 Super is Ada Lovelace; both run BF16, FP8, INT4 workloads in hardware. On price, the AMD MI300X lists from $2.99/GPU/hr and the RTX 4080 Super from $0.280/GPU/hr.

Which cloud providers offer the AMD MI300X and the RTX 4080 Super?

1 provider list the AMD MI300X (Hot Aisle) and 2 list the RTX 4080 Super (RunPod and SimplePod), across 1 and 2 regions respectively. No single provider currently lists both models.

How much does 1,000 GPU-hours cost on the AMD MI300X vs the RTX 4080 Super?

At the lowest rates listed today, 1,000 GPU-hours costs $2,990 on the AMD MI300X and $280 on the RTX 4080 Super, a difference of $2,710 for the same runtime. Rates are per GPU per hour and update hourly.

How this comparison is calculated

Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.

Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.

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