Quadro M4000 vs RTX 4080: Specs, VRAM & Price

Short answer: choose the RTX 4080 when 16 GB of VRAM is the gating requirement. Choose the Quadro M4000 when 8 GB is enough for the workload and the lower hourly rate points that way.

The Quadro M4000 has 8 GB of VRAM; the RTX 4080 has 16 GB.

You can rent both by the hour, no purchase required. Quadro M4000 from $0.069/GPU/hr; RTX 4080 from $0.173/GPU/hr. The Quadro M4000 is 60% cheaper at the entry rate.

Quadro M4000

Good for inference workloads on older-generation hardware

$0.069/hr
Lowest / GPU
$0.069/hr
Median / GPU
8 GB
VRAM
Maxwell
Architecture

RTX 4080

Good for inference and light fine-tuning workloads

$0.173/hr
Lowest / GPU
$0.297/hr
Median / GPU
16 GB
VRAM
Ada Lovelace
Architecture

Last updated: 2026-10-10 22:02:11 UTCRefreshes hourly

Specs side by side

SpecQuadro M4000RTX 4080
VRAM8 GB16 GB
Memory bandwidth–716.8 GB/s
ArchitectureMaxwellAda Lovelace
Compute capability5.28.9
Precisions in hardwareFP32, FP16FP32, FP16, BF16, FP8, INT4
Peak FP16/BF16 tensor TFLOPS–194.9 TFLOPS
Peak FP8 tensor TFLOPS–389.9 TFLOPS
Max board power (TDP)–320W
Form factorPCIePCIe
Regions13

On-demand price

RateQuadro M4000RTX 4080
Lowest per GPU/hr$0.069/GPU/hr (cheapest overall)$0.173/GPU/hr (cheapest overall)

Which is better for AI: Quadro M4000 or RTX 4080?

Choose the RTX 4080 when 16 GB of VRAM is the gating requirement. Choose the Quadro M4000 when 8 GB is enough for the workload and the lower hourly rate points that way.

Quadro M4000 vs RTX 4080: common questions

Is the Quadro M4000 or the RTX 4080 better for AI?

Short answer: choose the RTX 4080 when 16 GB of VRAM is the gating requirement. Choose the Quadro M4000 when 8 GB is enough for the workload and the lower hourly rate points that way.

Is the Quadro M4000 or the RTX 4080 cheaper to rent?

On Aquanode's live marketplace the Quadro M4000 starts at $0.069/GPU/hr (median $0.069/GPU/hr) and the RTX 4080 starts at $0.173/GPU/hr (median $0.297/GPU/hr). The Quadro M4000 is the cheaper of the two at the entry rate, by 60%.

What is the difference between the Quadro M4000 and the RTX 4080?

The Quadro M4000 has 8 GB of VRAM against the RTX 4080's 16 GB; the Quadro M4000 is a Maxwell part and the RTX 4080 is Ada Lovelace (compute capability 5.2 vs 8.9); only the RTX 4080 supports BF16, FP8, INT4 compute. On price, the Quadro M4000 lists from $0.069/GPU/hr and the RTX 4080 from $0.173/GPU/hr.

How widely available are the Quadro M4000 and the RTX 4080?

The Quadro M4000 is listed in 1 region and the RTX 4080 in 3 regions right now.

How much does 1,000 GPU-hours cost on the Quadro M4000 vs the RTX 4080?

At the lowest rates listed today, 1,000 GPU-hours costs $69 on the Quadro M4000 and $173 on the RTX 4080, a difference of $104 for the same runtime. Rates are per GPU per hour and update hourly.

How much VRAM does the Quadro M4000 have compared to the RTX 4080?

The Quadro M4000 has 8 GB of VRAM; the RTX 4080 has 16 GB.

How this comparison is calculated

Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.

Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.

Memory bandwidth, tensor TFLOPS, NVLink/interconnect and max board power are the same verified-from-datasheet figures shown on each model's own Quadro M4000 page and RTX 4080 page, which link the primary vendor source for that model. A dash here means Aquanode hasn't verified that figure from a primary source yet, never a guess.

Go further

Check what fits in each card's memory with the Quadro M4000 VRAM calculator and the RTX 4080 VRAM calculator, or browse every model by generation in the GPU index.

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