Quadro M4000 vs RTX 5080: Specs, VRAM & Price
Short answer: choose the RTX 5080 when 16 GB of VRAM is the gating requirement. Choose the Quadro M4000 when 8 GB is enough for the workload and the lower hourly rate points that way.
The Quadro M4000 has 8 GB of VRAM; the RTX 5080 has 16 GB.
You can rent both by the hour, no purchase required. Quadro M4000 from $0.069/GPU/hr; RTX 5080 from $0.416/GPU/hr. The Quadro M4000 is 83% cheaper at the entry rate.
Quadro M4000
Good for inference workloads on older-generation hardware
RTX 5080
Good for inference and light fine-tuning workloads
Last updated: 2026-10-10 22:02:22 UTCRefreshes hourly
Specs side by side
| Spec | Quadro M4000 | RTX 5080 |
|---|---|---|
| VRAM | 8 GB | 16 GB |
| Memory bandwidth | – | 960 GB/s |
| Architecture | Maxwell | Blackwell |
| Compute capability | 5.2 | 12.0 |
| Precisions in hardware | FP32, FP16 | FP32, FP16, BF16, FP8, INT4 |
| Peak FP16/BF16 tensor TFLOPS | – | 225.1 TFLOPS |
| Peak FP8 tensor TFLOPS | – | 450.2 TFLOPS |
| Max board power (TDP) | – | 360W |
| Form factor | PCIe | – |
| Regions | 1 | 2 |
On-demand price
| Rate | Quadro M4000 | RTX 5080 |
|---|---|---|
| Lowest per GPU/hr | $0.069/GPU/hr (cheapest overall) | $0.416/GPU/hr (cheapest overall) |
Which is better for AI: Quadro M4000 or RTX 5080?
Choose the RTX 5080 when 16 GB of VRAM is the gating requirement. Choose the Quadro M4000 when 8 GB is enough for the workload and the lower hourly rate points that way.
Quadro M4000 vs RTX 5080: common questions
Is the Quadro M4000 or the RTX 5080 better for AI?
Short answer: choose the RTX 5080 when 16 GB of VRAM is the gating requirement. Choose the Quadro M4000 when 8 GB is enough for the workload and the lower hourly rate points that way.
Is the Quadro M4000 or the RTX 5080 cheaper to rent?
On Aquanode's live marketplace the Quadro M4000 starts at $0.069/GPU/hr (median $0.069/GPU/hr) and the RTX 5080 starts at $0.416/GPU/hr (median $0.429/GPU/hr). The Quadro M4000 is the cheaper of the two at the entry rate, by 83%.
What is the difference between the Quadro M4000 and the RTX 5080?
The Quadro M4000 has 8 GB of VRAM against the RTX 5080's 16 GB; the Quadro M4000 is a Maxwell part and the RTX 5080 is Blackwell (compute capability 5.2 vs 12.0); only the RTX 5080 supports BF16, FP8, INT4 compute. On price, the Quadro M4000 lists from $0.069/GPU/hr and the RTX 5080 from $0.416/GPU/hr.
How widely available are the Quadro M4000 and the RTX 5080?
The Quadro M4000 is listed in 1 region and the RTX 5080 in 2 regions right now.
How much does 1,000 GPU-hours cost on the Quadro M4000 vs the RTX 5080?
At the lowest rates listed today, 1,000 GPU-hours costs $69 on the Quadro M4000 and $416 on the RTX 5080, a difference of $347 for the same runtime. Rates are per GPU per hour and update hourly.
How much VRAM does the Quadro M4000 have compared to the RTX 5080?
The Quadro M4000 has 8 GB of VRAM; the RTX 5080 has 16 GB.
How this comparison is calculated
Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.
Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.
Memory bandwidth, tensor TFLOPS, NVLink/interconnect and max board power are the same verified-from-datasheet figures shown on each model's own Quadro M4000 page and RTX 5080 page, which link the primary vendor source for that model. A dash here means Aquanode hasn't verified that figure from a primary source yet, never a guess.
Go further
Check what fits in each card's memory with the Quadro M4000 VRAM calculator and the RTX 5080 VRAM calculator, or browse every model by generation in the GPU index.
More Quadro M4000 comparisons
More RTX 5080 comparisons
Related reading: H100 pricing and specs, H100 vs H200, A100 vs H100, H100 and H200: SXM vs NVL vs PCIe, and The best GPUs for AI, ranked.
