RTX A6000 vs RTX PRO 4500 SE: Specs, VRAM & Price
Short answer: choose the RTX A6000 when 48 GB of VRAM is the gating requirement. Choose the RTX PRO 4500 SE when 32 GB is enough for the workload and availability points that way.
The RTX A6000 has 48 GB of VRAM; the RTX PRO 4500 SE has 32 GB.
You can rent both by the hour, no purchase required. RTX A6000 from $0.363/GPU/hr; RTX PRO 4500 SE from $0.792/GPU/hr. The RTX A6000 is 54% cheaper at the entry rate.
RTX A6000
Good for training and inference on models that don't need FP8 kernels
RTX PRO 4500 SE
Good for inference and light fine-tuning workloads
Last updated: 2026-10-10 18:37:00 UTCRefreshes hourly
Specs side by side
| Spec | RTX A6000 | RTX PRO 4500 SE |
|---|---|---|
| VRAM | 48 GB | 32 GB |
| Memory bandwidth | 768 GB/s | – |
| Architecture | Ampere | Blackwell |
| Compute capability | 8.6 | 12.0 |
| Precisions in hardware | FP32, FP16, BF16, INT4 | FP32, FP16, BF16, FP8, INT4 |
| NVLink / multi-GPU interconnect | NVLink, 2-way | – |
| Max board power (TDP) | 300W | – |
| Regions | 4 | 1 |
On-demand price
| Rate | RTX A6000 | RTX PRO 4500 SE |
|---|---|---|
| Lowest per GPU/hr | $0.550/GPU/hr | $0.792/GPU/hr |
Which is better for AI: RTX A6000 or RTX PRO 4500 SE?
Choose the RTX A6000 when 48 GB of VRAM is the gating requirement. Choose the RTX PRO 4500 SE when 32 GB is enough for the workload and availability points that way.
RTX A6000 vs RTX PRO 4500 SE: common questions
Is the RTX A6000 or the RTX PRO 4500 SE better for AI?
Short answer: choose the RTX A6000 when 48 GB of VRAM is the gating requirement. Choose the RTX PRO 4500 SE when 32 GB is enough for the workload and availability points that way.
Is the RTX A6000 or the RTX PRO 4500 SE cheaper to rent?
On Aquanode's live marketplace the RTX A6000 starts at $0.363/GPU/hr (median $0.627/GPU/hr) and the RTX PRO 4500 SE starts at $0.792/GPU/hr (median $0.792/GPU/hr). The RTX A6000 is the cheaper of the two at the entry rate, by 54%.
What is the difference between the RTX A6000 and the RTX PRO 4500 SE?
The RTX A6000 has 48 GB of VRAM against the RTX PRO 4500 SE's 32 GB; the RTX A6000 is an Ampere part and the RTX PRO 4500 SE is Blackwell (compute capability 8.6 vs 12.0); only the RTX PRO 4500 SE supports FP8 compute. On price, the RTX A6000 lists from $0.363/GPU/hr and the RTX PRO 4500 SE from $0.792/GPU/hr.
How widely available are the RTX A6000 and the RTX PRO 4500 SE?
The RTX A6000 is listed in 4 regions and the RTX PRO 4500 SE in 1 region right now.
How much does 1,000 GPU-hours cost on the RTX A6000 vs the RTX PRO 4500 SE?
At the lowest rates listed today, 1,000 GPU-hours costs $363 on the RTX A6000 and $792 on the RTX PRO 4500 SE, a difference of $429 for the same runtime. Rates are per GPU per hour and update hourly.
How much VRAM does the RTX A6000 have compared to the RTX PRO 4500 SE?
The RTX A6000 has 48 GB of VRAM; the RTX PRO 4500 SE has 32 GB.
How this comparison is calculated
Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.
Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.
Memory bandwidth, tensor TFLOPS, NVLink/interconnect and max board power are the same verified-from-datasheet figures shown on each model's own RTX A6000 page and RTX PRO 4500 SE page, which link the primary vendor source for that model. A dash here means Aquanode hasn't verified that figure from a primary source yet, never a guess.
Go further
Check what fits in each card's memory with the RTX A6000 VRAM calculator and the RTX PRO 4500 SE VRAM calculator, or browse every model by generation in the GPU index.
More RTX A6000 comparisons
More RTX PRO 4500 SE comparisons
Related reading: RTX A6000 pricing and specs, and RTX A6000 guide.
