RTX PRO 4500 SE vs RTX PRO 6000 SE: Specs, VRAM & Price
Short answer: choose the RTX PRO 6000 SE when 96 GB of VRAM is the gating requirement. Choose the RTX PRO 4500 SE when 32 GB is enough for the workload and the lower hourly rate points that way.
The RTX PRO 4500 SE has 32 GB of VRAM; the RTX PRO 6000 SE has 96 GB.
You can rent both by the hour, no purchase required. RTX PRO 4500 SE from $0.792/GPU/hr; RTX PRO 6000 SE from $2.15/GPU/hr. The RTX PRO 4500 SE is 63% cheaper at the entry rate.
RTX PRO 4500 SE
Good for inference and light fine-tuning workloads
RTX PRO 6000 SE
Good for training and serving frontier-scale LLMs
Last updated: 2026-10-10 18:03:58 UTCRefreshes hourly
Specs side by side
| Spec | RTX PRO 4500 SE | RTX PRO 6000 SE |
|---|---|---|
| VRAM | 32 GB | 96 GB |
| Memory bandwidth | – | 1,597 GB/s |
| Architecture | Blackwell | Blackwell |
| Compute capability | 12.0 | 12.0 |
| Precisions in hardware | FP32, FP16, BF16, FP8, INT4 | FP32, FP16, BF16, FP8, INT4 |
| Max board power (TDP) | – | Up to 600W (configurable) |
| Form factor | – | PCIe |
| Regions | 1 | 1 |
On-demand price
| Rate | RTX PRO 4500 SE | RTX PRO 6000 SE |
|---|---|---|
| Lowest per GPU/hr | $0.792/GPU/hr | $2.15/GPU/hr (cheapest overall) |
Which is better for AI: RTX PRO 4500 SE or RTX PRO 6000 SE?
Choose the RTX PRO 6000 SE when 96 GB of VRAM is the gating requirement. Choose the RTX PRO 4500 SE when 32 GB is enough for the workload and the lower hourly rate points that way.
RTX PRO 4500 SE vs RTX PRO 6000 SE: common questions
Is the RTX PRO 4500 SE or the RTX PRO 6000 SE better for AI?
Short answer: choose the RTX PRO 6000 SE when 96 GB of VRAM is the gating requirement. Choose the RTX PRO 4500 SE when 32 GB is enough for the workload and the lower hourly rate points that way.
Is the RTX PRO 4500 SE or the RTX PRO 6000 SE cheaper to rent?
On Aquanode's live marketplace the RTX PRO 4500 SE starts at $0.792/GPU/hr (median $0.792/GPU/hr) and the RTX PRO 6000 SE starts at $2.15/GPU/hr (median $2.15/GPU/hr). The RTX PRO 4500 SE is the cheaper of the two at the entry rate, by 63%.
What is the difference between the RTX PRO 4500 SE and the RTX PRO 6000 SE?
The RTX PRO 4500 SE has 32 GB of VRAM against the RTX PRO 6000 SE's 96 GB; both are Blackwell parts; both run BF16, FP8, INT4 workloads in hardware. On price, the RTX PRO 4500 SE lists from $0.792/GPU/hr and the RTX PRO 6000 SE from $2.15/GPU/hr.
How widely available are the RTX PRO 4500 SE and the RTX PRO 6000 SE?
The RTX PRO 4500 SE is listed in 1 region and the RTX PRO 6000 SE in 1 region right now.
How much does 1,000 GPU-hours cost on the RTX PRO 4500 SE vs the RTX PRO 6000 SE?
At the lowest rates listed today, 1,000 GPU-hours costs $792 on the RTX PRO 4500 SE and $2,148 on the RTX PRO 6000 SE, a difference of $1,356 for the same runtime. Rates are per GPU per hour and update hourly.
How much VRAM does the RTX PRO 4500 SE have compared to the RTX PRO 6000 SE?
The RTX PRO 4500 SE has 32 GB of VRAM; the RTX PRO 6000 SE has 96 GB.
How this comparison is calculated
Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.
Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.
Memory bandwidth, tensor TFLOPS, NVLink/interconnect and max board power are the same verified-from-datasheet figures shown on each model's own RTX PRO 4500 SE page and RTX PRO 6000 SE page, which link the primary vendor source for that model. A dash here means Aquanode hasn't verified that figure from a primary source yet, never a guess.
Go further
Check what fits in each card's memory with the RTX PRO 4500 SE VRAM calculator and the RTX PRO 6000 SE VRAM calculator, or browse every model by generation in the GPU index.
More RTX PRO 4500 SE comparisons
More RTX PRO 6000 SE comparisons
Related reading: H100 pricing and specs, H100 vs H200, A100 vs H100, H100 and H200: SXM vs NVL vs PCIe, and The best GPUs for AI, ranked.
