AMD MI300X vs RTX 4080: cloud rental cost compared
You can rent both by the hour, no purchase required. AMD MI300X from $2.99/GPU/hr across 1 provider; RTX 4080 from $0.158/GPU/hr across 2 providers. The RTX 4080 is 95% cheaper at the entry rate.
Specs side by side
Price by provider
AMD MI300X vs RTX 4080: common questions
Is the AMD MI300X or the RTX 4080 cheaper to rent?
On Aquanode's live marketplace the AMD MI300X starts at $2.99/GPU/hr (median $2.99/GPU/hr across 1 provider) and the RTX 4080 starts at $0.158/GPU/hr (median $0.270/GPU/hr across 2 providers). The RTX 4080 is the cheaper of the two at the entry rate, by 95%.
What is the difference between the AMD MI300X and the RTX 4080?
The AMD MI300X has 192 GB of VRAM against the RTX 4080's 16 GB; the AMD MI300X is a CDNA3 part and the RTX 4080 is Ada Lovelace; both run BF16, FP8, INT4 workloads in hardware. On price, the AMD MI300X lists from $2.99/GPU/hr and the RTX 4080 from $0.158/GPU/hr.
Which cloud providers offer the AMD MI300X and the RTX 4080?
1 provider list the AMD MI300X (Hot Aisle) and 2 list the RTX 4080 (Akash and RunPod), across 1 and 2 regions respectively. No single provider currently lists both models.
How much does 1,000 GPU-hours cost on the AMD MI300X vs the RTX 4080?
At the lowest rates listed today, 1,000 GPU-hours costs $2,990 on the AMD MI300X and $158 on the RTX 4080, a difference of $2,833 for the same runtime. Rates are per GPU per hour and update hourly.
How this comparison is calculated
Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.
Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.