AMD MI300X vs RTX 4090: cloud rental cost compared

You can rent both by the hour, no purchase required. AMD MI300X from $2.99/GPU/hr across 1 provider; RTX 4090 from $0.340/GPU/hr across 3 providers. The RTX 4090 is 89% cheaper at the entry rate.

AMD MI300X
Good for training and serving frontier-scale LLMs
$2.99/hr
Lowest / GPU
$2.99/hr
Median / GPU
192 GB
VRAM
CDNA3
Architecture
RTX 4090
Good for inference and light fine-tuning workloads
$0.340/hr
Lowest / GPU
$0.522/hr
Median / GPU
24 GB
VRAM
Ada Lovelace
Architecture

Specs side by side

Spec
AMD MI300X
RTX 4090
VRAM
192 GB
24 GB
Architecture
CDNA3
Ada Lovelace
Compute capability
n/a
8.9
Precisions in hardware
FP32, FP16, BF16, FP8, INT4
FP32, FP16, BF16, FP8, INT4
Interconnect
PCIe
PCIe 4.0 x16
Lowest $/GPU/hr
$2.99
$0.340
Median $/GPU/hr
$2.99
$0.522
Providers
1
3
Regions
1
3

Price by provider

Provider
AMD MI300X $/GPU/hr
RTX 4090 $/GPU/hr
RunPod
$0.340
SimplePod
$0.350
Akash
$0.452
Hot Aisle
$2.99

AMD MI300X vs RTX 4090: common questions

Is the AMD MI300X or the RTX 4090 cheaper to rent?

On Aquanode's live marketplace the AMD MI300X starts at $2.99/GPU/hr (median $2.99/GPU/hr across 1 provider) and the RTX 4090 starts at $0.340/GPU/hr (median $0.522/GPU/hr across 3 providers). The RTX 4090 is the cheaper of the two at the entry rate, by 89%.

What is the difference between the AMD MI300X and the RTX 4090?

The AMD MI300X has 192 GB of VRAM against the RTX 4090's 24 GB; the AMD MI300X is a CDNA3 part and the RTX 4090 is Ada Lovelace; both run BF16, FP8, INT4 workloads in hardware. On price, the AMD MI300X lists from $2.99/GPU/hr and the RTX 4090 from $0.340/GPU/hr.

Which cloud providers offer the AMD MI300X and the RTX 4090?

1 provider list the AMD MI300X (Hot Aisle) and 3 list the RTX 4090 (RunPod, SimplePod and Akash), across 1 and 3 regions respectively. No single provider currently lists both models.

How much does 1,000 GPU-hours cost on the AMD MI300X vs the RTX 4090?

At the lowest rates listed today, 1,000 GPU-hours costs $2,990 on the AMD MI300X and $340 on the RTX 4090, a difference of $2,650 for the same runtime. Rates are per GPU per hour and update hourly.

How this comparison is calculated

Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.

Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.

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