AMD MI300X vs RTX PRO 5000: cloud rental cost compared

You can rent both by the hour, no purchase required. AMD MI300X from $2.99/GPU/hr across 1 provider; RTX PRO 5000 from $0.820/GPU/hr across 1 provider. The RTX PRO 5000 is 73% cheaper at the entry rate.

AMD MI300X
Good for training and serving frontier-scale LLMs
$2.99/hr
Lowest / GPU
$2.99/hr
Median / GPU
192 GB
VRAM
CDNA3
Architecture
RTX PRO 5000
Good for fine-tuning mid-size models and high-throughput inference
$0.820/hr
Lowest / GPU
$0.820/hr
Median / GPU
48 GB
VRAM
Blackwell
Architecture

Specs side by side

Spec
AMD MI300X
RTX PRO 5000
VRAM
192 GB
48 GB
Architecture
CDNA3
Blackwell
Compute capability
n/a
12.0
Precisions in hardware
FP32, FP16, BF16, FP8, INT4
FP32, FP16, BF16, FP8, INT4
Interconnect
PCIe
Lowest $/GPU/hr
$2.99
$0.820
Median $/GPU/hr
$2.99
$0.820
Providers
1
1
Regions
1
1

Price by provider

Provider
AMD MI300X $/GPU/hr
RTX PRO 5000 $/GPU/hr
RunPod
$0.820
Hot Aisle
$2.99

AMD MI300X vs RTX PRO 5000: common questions

Is the AMD MI300X or the RTX PRO 5000 cheaper to rent?

On Aquanode's live marketplace the AMD MI300X starts at $2.99/GPU/hr (median $2.99/GPU/hr across 1 provider) and the RTX PRO 5000 starts at $0.820/GPU/hr (median $0.820/GPU/hr across 1 provider). The RTX PRO 5000 is the cheaper of the two at the entry rate, by 73%.

What is the difference between the AMD MI300X and the RTX PRO 5000?

The AMD MI300X has 192 GB of VRAM against the RTX PRO 5000's 48 GB; the AMD MI300X is a CDNA3 part and the RTX PRO 5000 is Blackwell; both run BF16, FP8, INT4 workloads in hardware. On price, the AMD MI300X lists from $2.99/GPU/hr and the RTX PRO 5000 from $0.820/GPU/hr.

Which cloud providers offer the AMD MI300X and the RTX PRO 5000?

1 provider list the AMD MI300X (Hot Aisle) and 1 list the RTX PRO 5000 (RunPod), across 1 and 1 region respectively. No single provider currently lists both models.

How much does 1,000 GPU-hours cost on the AMD MI300X vs the RTX PRO 5000?

At the lowest rates listed today, 1,000 GPU-hours costs $2,990 on the AMD MI300X and $820 on the RTX PRO 5000, a difference of $2,170 for the same runtime. Rates are per GPU per hour and update hourly.

How this comparison is calculated

Every price is normalized to a per-GPU hourly rate using the same pipeline as every other pricing surface on Aquanode, and only the cheapest qualifying offer per provider is shown. A dash means that provider does not currently list that GPU.

Architecture, compute capability and supported precisions come from each vendor's published datasheet for that generation, not from the marketplace feed. This page regenerates at most once per hour.

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